Purine nucleotides
Sigma Aldrich Fine Chemicals Biosciences Adenosine Quantification A
Adenosine is a purine nucleoside base which is the precursor of adenosine triphosphate or ATP and is utilized thoroughly throughout the entire body in general metabolism. Extracellular adenosine acts as a local modulator with a generally cytoprotective function in the body. Its effects on tissue protection and repair fall into four categories increasing the ratio of oxygen supply to demand protecting against ischaemic damage by cell conditioning triggering anti-inflammatory responses and the promotion of angiogenesis.
Cayman Chemical AdenosIn 5-monphosphates 1g
A central nucleotide with functions in metabolism and cell signaling
Medchemexpress LLC Adenosine receptor antagonist 3 | 2400864-80-2 | 97.1% | C16H14N6S | 10MG
Adenosine receptor antagonist 3 is a small-molecule research compound that antagonizes adenosine receptors and is used in in vitro pharmacology and GPCR/G protein signaling studies. Supplied as a light-yellow solid and as a 10 mM solution in DMSO, it has a reported purity of 97.1% and molecular formula C16H14N6S.
Apexbio Technology LLC Motesanib Diphosphate (AMG-706) 857876-30-3 100mg
Motesanib Diphosphate (AMG-706 CAS 857876-30-3) is an oral small-molecule ATP-competitive inhibitor that targets vascular endothelial growth factor receptors (VEGFR1/2/3) platelet-derived growth factor receptor (PDGFR) c-Kit and Ret with reported IC50 values of 2 84 nM It demonstrates over 1000-fold selectivity for VEGFRs relative to EGFR Src and p38 kinases In vitro Motesanib Diphosphate potently inhibits VEGF-induced proliferation of human endothelial cells (IC50 10 nM) and blocks PDGF- and SCF-induced signaling while showing minimal effects on bFGF-stimulated proliferation In preclinical studies it suppresses angiogenesis and induces regression in tumor xenograft models Motesanib is under investigation in anti-angiogenic cancer research
Selleck Chemical LLC Oritavancin Diphosphate-5MG
Oritavancin Diphosphate is an orally active glycopeptide antibiotic which is active against Gram-positive bacteria and also has antibacterial activity against multidrug-resistant Streptococcus pneumoniae
Medchemexpress LLC 6-O-methyl guanosine | 7803-88-5 | MFCD01723912 | 99.7% | 297.27 g·mol⁻1 | C11H15N5O5 | 5 MG
6-O-methyl guanosine is a modified nucleoside for biochemical research, reported to inhibit colony-forming ability in certain xeroderma pigmentosum cell lines. It is supplied as a solid reagent intended for in vitro studies and analytical applications.
- High purity (99.7%) suitable for analytical and biological experiments.
- Molecular weight 297.27 g·mol⁻1; formula C11H15N5O5.
- Soluble in DMSO (130 mg/mL); sparingly soluble in water (2 mg/mL); ultrasonic or warming recommended to aid dissolution.
- Stable as a powder at -20°C for extended storage.
- Available in small research quantities (for example, 5 mg) for laboratory use.
Medchemexpress LLC Cidofovir diphosphate tri(triethylamine) | 00-00-0 | 99.9% | 742.72 g/mol | C26H61N6O12P3 | 5 MG
Cidofovir diphosphate tri(triethylamine) is the triethylamine salt of cidofovir diphosphate, an active intracellular metabolite and selective inhibitor of viral DNA polymerases. It is provided as a high-purity biochemical reagent intended for in vitro and biochemical research applications.
Medchemexpress LLC Adenosine antagonist-1 | 431040-19-6 | 99.8% | 359.41 g·mol⁻¹ | C18H13N7S | 5 MG
Adenosine antagonist-1 is a small-molecule adenosine A3 receptor (AA3R) antagonist with reported anti-inflammatory activity. The compound is supplied in solid and solution formats for research use and is supported by analytical data including HPLC, LCMS, and NMR (CAS 431040-19-6; formula C18H13N7S; MW 359.41).
- Selective adenosine A3 receptor antagonist suitable for inflammatory research.
- Characterized by CAS and molecular data for reproducibility.
- Available as solid quantities and as a 10 mM solution in DMSO for assays.
- High purity suitable for biochemical and cell-based assays.
- Analytical documents provided including HPLC, LCMS, and NMR.